with any hack, there is never a garuntee that you will never get banned while hacking (or not hacking and just playing really really well, if they want to be a-holish enough about it) but from what i know, running via python is the safest way and is currently undectable by vac, so this is as close are you can get to a garuntee of no ban. but i stress <bold> when hacking, you MAY be banned</bold> regardless of the hack you are using because you are breaking the rules.
i would assume that he is referring to closing the hack as it seems that in your situation it is causing some form of misread from the server. So in between games he is saying that you need to close the hack and rerun as he said to.