Move the mouse to a different USB port . If you are using an external USB hub or pass through device please disable it for trouble shooting and plug the mouse directly in to the system. If you have connected the mouse using a USB to PS/2 converter please power your system off and remove the PS/2 converter and reconnect to a USB port or it could be power settings go to Control Panel: "Power options" > "Change plan settings" > "Advanced power options" > "USB Settings". Disable "Selective supspending"