Relic Shield 90% of the time. Ancient Coin doesn't offer any good laning stats, while Relic Shield offers health and a way to sustain from the 40 HP health execute. However, the upgrade (Nomad's Medallion) gives MS and may help against ranged champs (buying boots early would be the better option though). Buying the Talisman of Ascension is usually done if you need disengage/engage when your current team composition offers little of both. Nevertheless if you are already in this situation, I would buy the Relic Shield early (and possibly its upgrade), then sell it and start building the Talisman of Ascension once laning phase ends.