Sure you can: Look at the ICDBurn interface for straight up 'file copy' like operation like you would through windows:
ICDBurn Interface ()
Sample App step by step:
https://www.codeguru.com/csharp/.net/...le.php/c15201/
or the Image Mastering API (IMAPI) if you want more control:
Image Mastering API (Windows)
sample:
https://www.codeprojec*****m/KB/cs/IsoBurner.aspx