Go to Cross Fire and then to Options.And do it Full Screen Mode.
If still doesn't help this may help you:
Almost every monitor and graphics card driver has a setting for this on VGA connections, not all, but a very large majority. When playing ingame with black bars on your screen, go into your monitor settings and look for anything related to Scaling. If you come across something with "Scaling" in it's name, change the default setting (so if it's off, turn it on and if it's on, turn it off.) And that should fix the problem. If not, go into your Driver settings (most every updated card has its own control panel now) and look for similar settings in your resolution regarding scaling.
(With almost all nVidia cards [with updated drivers] you can just Right Click on your Desktop and select "NVidia Control Panel" and from there look at resolution settings)