PayPal Chargeback

Is there a way to avoid PayPal charge-backs and disputes? Especially with larger transactions. I've tried splitting up the payments but i'm not sure if that'll work.

There is no way you can avoid charge back, buyer can charge back any time and win. However, to avoid losing money, you can simply make a secondary fake info Paypal account and transfer all your money to it, unless your primary Paypal account have real info, Paypal will find you easily and make you pay. Or you can use the secondary fake info Paypal to receive money and transfer to your main, that way your fake account take consequences but they don't know who's the real owner, so you can just run away. This method is not 100% Guaranteed that it will work, but I've done it before. Use VPN on fake account if paranoid.