Buy 4x PNY XLR8 8800 Ultras and quad SLI them on a Gigabyte GA-8N Royal motherboard. And then buy a SSD 500GB and another 500GB 10K RPM Velociraptor Seagate Hard Drive.
And then a 1TB Hard drive for porn space.
Get 8GB DDR3 Corsair RAM and buy Windows 7 Ultimate 64-bit.
With liquid cooling of course.
At 1 grand per card, that would make your computer at least 4K+.