Open Cross Fire and open task manager. Go to process list and find "crossfire.exe" Then right click and choose Set Affinity. Tick CPU0 only. If you got CPU1 untick it.
go here : [SOLVED] HAVE SHAKY/WOBBLY MOUSE MOVEMENTS? Slant has a fix for you! - Z8Games or http://forum.z8games.com/showthread.php?t=128163
It happenned to me in the past. It was because I didn't have a good FPS. Try to get a better GFX card, or follow that tutorial : [SOLVED] HAVE SHAKY/WOBBLY MOUSE MOVEMENTS? Slant has a fix for you! - Z8Games