That's debugger detection, it won't allow you to launch the game if you have any debugger opened or if you open a debugger in middle of game it will crash.
1) If you're attempting to hack, I won't recommend you to attach _MAS.exe to the debugger, first create a dump file then proceed removing Themida protection.
2) If you're just using a hack posted here I have no clue why it detect it, since the hacks are D3D or trainers and have nothing to be with debugging, try restarting your PC and what Ad litteram said.
Common debuggers are;
IDA PRO.
Olly
Kernel
CheatEngine debugger...