problem with warframe is that its an indie game, therefore there are less players, less players overall means more of a possibility for a crc check. Never mess with a smaller game like this, if you do everything client side, they cannot prove your illegitimacy. However once you start messing with things like alerts which are server sided, they can clearly state that there is no legitimate possibility of you running an alert mission that many times.
I found a way to completely destroy this game (on accident actually) however, i love the developers approach of non p2p style therefore i dont feel like addressing it as of yet.