I keep mine at 25%, it's saved me around 2-4 times per character, and when I do die it's normally due to lag/stacked bullets or a shotgun, so raising it beyond that point is pointless in my opinion; for example, I find 35%-40% will nexus me out of a tomb when I'm perfectly fine, but 25% will save me when I need it to and only when I need it to. This is especially true if you're on a class that isn't very squishy; 40% on a char with 950 hp and around 50 def is just serious overkill and if you don't have a decent pet could even get you nexused out of abbys unnecessarily.