Making a gui in python is easy... but you need to download a gui library and you need to plan your thing.
QtDesigner (it come with PyQt4) is an alternative if you want to create a gui using drag and drop tool.
[IMG]http://www.developer.noki*****m/Community/Wiki/images/thumb/5/51/Qt-creator-new-mobile-qt-project-6.png/500px-Qt-creator-new-mobile-qt-project-6.png[/IMG]